Which type of adiposity is considered most inflammatory?

Central (visceral) adiposity is considered the most inflammatory type of fat tissue. This is primarily due to its location within the abdominal cavity, where it surrounds vital organs such as the liver, pancreas, and intestines. Visceral fat is known to produce a higher amount of pro-inflammatory cytokines and adipokines, which are signaling molecules that can lead to chronic inflammation and contribute to various health issues, such as insulin resistance, cardiovascular disease, and metabolic syndrome.

In contrast, subcutaneous adiposity, which is located just beneath the skin, usually exhibits a more favorable metabolic profile and tends to be less inflammatory. Peripheral adiposity, typically found in areas such as the hips and thighs, is also associated with lower levels of inflammation compared to central adiposity. Comparative adiposity is not a recognized type in this context and does not apply to the discussion of adiposity-related inflammation. Therefore, the prominence of visceral fat in inflammatory processes makes central adiposity the most relevant choice for this question.