What is the primary effect of statin medications on lipid levels?

The primary effect of statin medications on lipid levels is to decrease low-density lipoprotein (LDL) cholesterol and triglycerides while potentially increasing high-density lipoprotein (HDL) cholesterol. Statins work by inhibiting the enzyme HMG-CoA reductase, which plays a central role in the biosynthesis of cholesterol in the liver. This leads to a reduction in overall cholesterol production and an increase in the liver's uptake of LDL from the bloodstream, resulting in lower LDL levels.

Additionally, while the primary aim of statins is to reduce LDL cholesterol due to its strong association with cardiovascular disease, some studies have shown that statins can also have a modest impact on increasing HDL levels. However, the most significant and well-documented effects of statins are the reduction of LDL and triglycerides, which are crucial to lowering the risk of atherosclerosis and cardiovascular events.

In summary, option B accurately reflects the primary action of statins in managing lipid levels effectively, aligning with the established understanding of their therapeutic effects in clinical practice.