Some of the newest emerging risk factors for coronary artery disease include:

The selection of homocysteine, lipoprotein, and fibrinogen as emerging risk factors for coronary artery disease is particularly significant as these markers have garnered attention in recent research for their potential association with cardiovascular health.

Homocysteine is an amino acid that, at elevated levels, has been linked to increased risk of coronary artery disease. High levels of homocysteine may damage the arterial walls and promote atherogenesis (the formation of fatty plaques in the arteries).

Lipoprotein(a) is a variant of LDL cholesterol that is genetically determined and can contribute to the development of coronary artery disease, often independently of other lipid risk factors. Elevated levels of lipoprotein(a) are associated with a higher risk of atherosclerosis.

Fibrinogen is a blood plasma protein that is involved in the clotting process. Elevated fibrinogen levels can indicate increased inflammation and a heightened risk of thrombus formation, thereby increasing the risk of heart attacks and other cardiovascular events.

These emerging risk factors highlight the complexity of coronary artery disease and emphasize that traditional risk factors, while important, may not account for the entirety of an individual's risk profile. Monitoring these newer markers can help practitioners better assess and manage a patient’s cardiovascular health.